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Supplement Reviews
Simmondsin (jojoba oil)
Jojoba oil has been used for years in cosmetic preparations but this
particular extract has special effects. This special herbal extract
has potential for powerful appetite suppression effects. Deceased
food intake can be a key to fat and weight loss and this ingredient
has potential to be one of the most powerful appetite suppressors
around. In fact, one of the main ways that ephedrine/caffeine
combinations seem to boost weight/fat loss is through appetite
suppression. In the 1990s, Belgian researcher Marnix Cokelaere
discovered that simmondsin was acting as a hunger satiety
ingredient. This allowed him to reinterpret earlier experiments with
mice and cattle fed diets supplemented with jojoba meal. This
ingredient satisfied the animals' hunger, causing the decline in
feed intake. In fact, many animal studies show the powerful
appetite suppression effects of this ingredient. Food intake was
decreased significantly in many experiments with animals. In one
study published in the British Journal of Nutrition,
researchers verified a significant reduction in food intake in the
simmondsin group of rats. This effect was even greater in obese
rats. Simmondsin seems to work by allowing the body to stay
full longer and thus control satiety. Simmondsin is thought to
either directly stimulate CCK (Cholecystokinin), a hormone that
helps control food intake and seems to slow gastric motility,
release or bind to the same receptors as CCK. The animal studies
have used fairly high doses. Some studies suggest
that it might lower thyroid hormone which would in turn lower
metabolism—not good. There is a big “if” in humans but this
ingredient does have potential and future human studies will be done
to see if it as efficacious in humans as it is in animals. Stay
tuned!
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